Coordination Behavior and Biopotency of N and S/O Donor Ligands with their Palladium(II) and Platinum(II) Complexes

R.V. Singh*, N. Fahmi and M.K. Biyala

Department of Chemistry, University of Rajasthan, Jaipur-302004, India

Some metal complexes of Schiff bases have been prepared by the interactions  of  palladium(II) and platinum(II) chloride with 5-chloro-1,3-dihydro-3-[2-(phenyl)-ethylidene]-2H-indol-2-one-hydrazinecarbothioamide(L¹H) and 5-chloro-1,3-dihydro-3-[2(phenyl)-ethylidene]-2H-indol-2-one-hydrazinecarboxamide(L²H), in bimolar ratios. All the new compounds have been characterized by elemental analyses, conductance measurements, molecular weight determinations, IR and ¹H NMR spectral studies. The spectral data are consistent with a square planar geometry around Pd(II) and Pt(II) in which the ligands act as neutral bidentate and monobasic bidentate ligands, coordinating through the nitrogen and sulfur/oxygen atoms. Free ligands and their metal complexes were screened for their antimicrobial activity on different species of pathogenic fungi and bacteria and their biopotency has been discussed.

Keywords: Schiff bases, Palladium(II) and Platinum(II) chlorides, Fungicidal and bactericidal activities