M.R. Saidi^a,*, R. Stan Brown^b,* and A. Ziyaei-Halimjani^a

^bDepartment of Chemistry, Queen’s University, Kingston, Ontario, Canada

^aDepartment of Chemistry, Department of Chemistry, Sharif University of Technology,

P.O. Box 11365-9516 Tehran, Iran

(Received 6 October 2006, Accepted 12 November 2006)

A one-pot high yielding reductive amination of aldehydes with primary and secondary amines using LiClO₄/NaBH₄ and LiClO₄/LiAlH₄ as reducing agents in diethyl ether is described.

Keywords: Reductive amination, Sodium borohydride, Lithium aluminum hydride, Lithium perchlorate, Aldehyde