PEG-SO₃H as a New, Highly Efficient and Homogeneous Polymeric Catalyst for the Synthesis of Bis(indolyl)methanes and 4,4′×-(Arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s in Water

A. Hasaninejad^a,, M. Shekouhy^a, A. Zare^b,, S.M.S. Hoseini Ghattali^a and N. Golzar^a

^aDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
^bDepartment of Chemistry, Payame Noor University (PNU), Iran

In this work, a green, simple and highly efficient procedure for the synthesis of bis(indolyl)methanes and 4,4′×-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s [as an important class of bis(pyrazolyl)methanes] is described. The condensation of indoles or 1-phenyl-3-methylpyrazol-5-one with carbonyl compounds catalyzed by poly(ethylene glycol)-bound sulfonic acid (PEG-SO₃H) in water affords the title compounds in high yields and relatively short reaction times.

Keywords: Poly(ethylene glycol)-bound sulfonic acid (PEG-SO₃H), Bis(indolyl)methane, Bis(pyrazolyl)methane, 4,4′×-(Arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol), Polymeric catalyst

PEG-SO3H as a New, Highly Efficient and Homogeneous Polymeric Catalyst for the Synthesis of Bis(indolyl)methanes and 4,4′×-(Arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s in Water

A. Hasaninejada,*, M. Shekouhya, A. Zareb,*, S.M.S. Hoseini Ghattalia and N. Golzara

aDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran bDepartment of Chemistry, Payame Noor University (PNU), Iran

PEG-SO₃H as a New, Highly Efficient and Homogeneous Polymeric Catalyst for the Synthesis of Bis(indolyl)methanes and 4,4′×-(Arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s in Water

A. Hasaninejad^a,, M. Shekouhy^a, A. Zare^b,, S.M.S. Hoseini Ghattali^a and N. Golzar^a

^aDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
^bDepartment of Chemistry, Payame Noor University (PNU), Iran