Boric acid Catalyzed Efficient Synthesis of Symmetrical N,N’-Alkylidene Bisamides

G. Harichandran^a,,S. DavidAmalraj^a and P. Shanmugam^b,

^aDepartment of Polymer Science, University of Madras, Guindy Campus, Chennai-600 025, India
^bOrganic Chemistry Laboratory, Central Leather Research Institute, Adyar, Chennai-600 020, India

Symmetrical N,N’-alkylidene bisamides were synthesized in excellent yield by condensation of aromatic aldehydes and amides in the presence of boric acid as a catalyst under thermal and neat microwave irradiation conditions. It is the first successful report of boric acid has been used as Lewis acid catalyst for the preparation of symmetrical N,N’-alkylidene bisamides. The remarkable advantages offered by this method are green catalyst, mild reaction condition, simple procedure, fast reaction and moderate to good yield of products.

Keywords: N,N’-Alkylidene bisamides, Amides, Aldehydes, Boric acid

Boric acid Catalyzed Efficient Synthesis of Symmetrical N,N’-Alkylidene Bisamides

G. Harichandrana,*, S. David Amalraja and P. Shanmugamb,*

aDepartment of Polymer Science, University of Madras, Guindy Campus, Chennai-600 025, India bOrganic Chemistry Laboratory, Central Leather Research Institute, Adyar, Chennai-600 020, India

G. Harichandran^a,,S. DavidAmalraj^a and P. Shanmugam^b,

^aDepartment of Polymer Science, University of Madras, Guindy Campus, Chennai-600 025, India
^bOrganic Chemistry Laboratory, Central Leather Research Institute, Adyar, Chennai-600 020, India