J. Iran. Chem. Soc., Vol. 7, No. 1 March 2010, pp.95~99.

Current location: JICS Archive > Vol. 7 > No. 1 > Articles : 8

Zr(HSO4)4/SiO2: An Effective Heterogeneous Alternative for One-Pot Synthesis of β-Acetamido Ketones


B.F. Mirjalilia,*, A. Bamonirib, M.A. Karimi Zarchia and H. Emtiazia


aDepartment of Chemistry, College of Science, Yazd University, 89195-741, Yazd, Iran
bDepartment of Chemistry, College of Science, University of Kashan, Kashan, Iran


     In a one-pot procedure, enolizable ketones reacted with aromatic aldehydes, acetyl chloride and acetonitrile at room temperature in the presence of Zr(HSO4)4/SiO2 to furnish the corresponding β-acetamido ketones in improved yields.


Keywords: Zr(HSO4)4/SiO2, β-Acetamido ketones, One-pot method, Multi-component reaction, Room temperature

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