Silica-Supported LiHSO₄ as a Highly Efficient, Heterogeneous and Reusable Catalytic System for the Solvent-Free Synthesis of β-Enaminones and β-Enamino Esters

A. Hasaninejad^a,, A. Zare^b,, M.R. Mohammadizadeh^aand M. Shekouhy^a

^aDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
^bDepartment of Chemistry, Payame Noor University (PNU), Iran

A highly efficient, simple and green procedure for the synthesis of β-enaminones and β-enamino esters is described. The reaction of aromatic and aliphatic amines with β-dicarbonyl compounds using catalytic amount of silica-supported LiHSO₄ (LiHSO₄/SiO₂) under solvent-free conditions at 80 °C affords the title compounds in high to excellent yields and in short reaction times.

Keywords: LiHSO₄/SiO₂, Solvent-free, β-Enaminone, β-Enamino ester, β-Dicarbonyl compound, Green chemistry

Silica-Supported LiHSO4 as a Highly Efficient, Heterogeneous and Reusable Catalytic System for the Solvent-Free Synthesis of β-Enaminones and β-Enamino Esters

A. Hasaninejada,*, A. Zareb,*, M.R. Mohammadizadehaand M. Shekouhya

aDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran bDepartment of Chemistry, Payame Noor University (PNU), Iran

Silica-Supported LiHSO₄ as a Highly Efficient, Heterogeneous and Reusable Catalytic System for the Solvent-Free Synthesis of β-Enaminones and β-Enamino Esters

A. Hasaninejad^a,, A. Zare^b,, M.R. Mohammadizadeh^aand M. Shekouhy^a

^aDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
^bDepartment of Chemistry, Payame Noor University (PNU), Iran