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Synthetic, Structural and Biological Studies of Organotin(IV) Complexes of Schiff Bases Derived from Pyrrol-2-carboxaldehyde

K. Singh^a,*, Dharampal^a and S.S. Dhiman^b

^aDepartment of Chemistry, Kurukshetra University, Kurukshetra-136 119, Haryana, India
^bDepartment of Biotechnology,Kurukshetra University, Kurukshetra-136 119, Haryana, India

Some new organotin(IV) complexes having general formulae R₂MCl[L] and R₂M[L]₂ were synthesized by the reactions of Me₂MCl₂ with Schiff bases [5-Mercapto-4-(pyrrolcarboxalideneamino)-s-triazole, 5-Mercapto-3-methyl-4-(2-pyrrol-carboxalideneamino)-s-triazole, 3-Ethyl-5-mercapto-4-(2-pyrrolcarboxalideneamino)-s-triazole] in 1:1 and 1:2 molar ratios. All of the compounds were characterized by elemental analysis, molar conductance, IR, UV, ¹H, ¹³C and ¹¹⁹Sn NMR spectral studies. The IR and ¹H NMR spectral data suggest the involvement of azomethine nitrogen in coordination with the central metal atom. With the help of the above-mentioned spectral studies, penta and hexacoordinated environments around the central metal atoms in the 1:1 and 1:2 complexes, respectively, have been proposed. Finally, the free ligands and their metal complexes were tested in vitro against some pathogenic bacteria and fungi to assess their antimicrobial properties.

Keywords: Organotin(IV) complexes, s-Triazoles, Schiff bases, Antifungal and antibacterial activities