Current location: JICS Archive > Vol. 6 > No. 3 > Articles : 5

Basic Resin Mediated Efficient One-Pot Synthesis of Carbazates from the Corresponding Alkyl Halides

D. Chaturvedi^a,*, A.K. Chaturvedi^b, N. Mishra^b and V. Mishra^b

^aBio-Organic Chemistry Division, Indian Institute of Integrative Medicine, Canal Road, Jammu-Tawi-180001, J. & K.,India
^bSynthetic Research Laboratory, Department of Chemistry, B. S. A. P. G. College, Mathura-281004, U. P.,India

A quick and efficient, one-pot synthesis of carbazates was accomplished in high yields by the reaction of various primary, secondary, and tertiary alkyl halides with a variety of substituted hydrazines using Amberlite IRA 400 basic resin/CO₂ system. The reaction conditions were mild with simpler work-up procedures than the previously reported methods.

Keywords: Alkyl halides, Basic resin, Carbon dioxide, Substituted hydrazines, Carbazates